Barrett, The Honors College Thesis/Creative Project Collection

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Nerve endings are particularly difficult to target during peripheral nerve block (PNB) procedures, so ultrasound-guided needles are of immense importance to guarantee safe and efficient delivery of the anesthetic to the target nerve. Despite significant progress in needle visualization with ultrasound imaging, there are still several factors that lead to poor needle visibility, the main factor being insertion angle. Introducing cavities and holes in the needle at specific intervals through pitting corrosion may alter the ultrasonic feedback from the sensor, thereby resulting in improved clarity of the reconstructed image. The purpose of this experiment is to investigate the effectiveness of ...

Contributors
Tze, David, Muthuswamy, Jit, Towe, Bruce, et al.
Created Date
2016-05

Phosphoinositol-Dependent Kinase 1 (PDK1) acts in conjunction with phosphorylated lipids such as Phosphoinositol-3,4,5-triphosphate (PIP3) to activate a variety of proteins that regulate mechanisms ranging from cell growth and survival to cytoskeletal rearrangement. In this investigation PDK1 was examined in the context of cellular division. The techniques of immunocytochemistry and live cell imaging were used to visualize the effects of the inhibition of PDK1 on division in HeLa cells. Division was impaired at metaphase of mitosis. The inhibited cells were unable to initiate anaphase cell-elongation ultimately leading to the flattening of spherical, metaphase cells. Preliminary studies with imunocytochemistry and live cell ...

Contributors
Masserano, Benjamin Max, Capco, David, Baluch, Debra, et al.
Created Date
2014-05

Background: The American Heart Association has created an Official 2012 Hands-Only CPR Instructional Video that is approximately one minute in length and has been viewed over 600,000 times on YouTube. Objective: To evaluate the video’s effectiveness in teaching adolescents aged 12-17 hands-only CPR. Methodology: The study took place in the Phoenix metropolitan area. Study participants were recruited from high schools, junior high schools and the Tempe Boys & Girls Club. The 100 study participants took a short, four question survey and watched video on either a laptop computer or video projector. Participants were then subjected to a cardiac arrest mock ...

Contributors
Choppi, Joseph Anthony, Johnston, Carol, Hall, Rick, et al.
Created Date
2013-05

Cancer modeling has brought a lot of attention in recent years. It had been proven to be a difficult task to model the behavior of cancer cells, since little about the ”rules” a cell follows has been known. Existing models for cancer cells can be generalized into two categories: macroscopic models which studies the tumor structure as a whole, and microscopic models which focus on the behavior of individual cells. Both modeling strategies strive the same goal of creating a model that can be validated with experimental data, and is reliable for predicting tumor growth. In order to achieve this ...

Contributors
Han, Zimo, Motsch, Sebastien, Moustaoui, Mohamed, et al.
Created Date
2016-12

Barrett, the Honors College accepts high performing, academically engaged students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project, supervised and defended in front of a faculty committee. The thesis or creative project allows students to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is a student’s opportunity to explore areas of academic interest with greater intensity than is possible in a single course. It is also an opportunity to engage with professors, nationally recognized in their fields and specifically interested and committed to working with honors students. This work provides tangible evidence of a student’s research, writing and creative skills to graduate schools and/or prospective employers.