Barrett, The Honors College Thesis/Creative Project Collection

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2000 2018

Nicotine addiction remains a prevalent public health issue, and the FDA has released a statement outlining the systematic reduction of nicotine to non-zero levels in the coming years. Current research has not yet established the effects of abrupt nicotine dose reduction on vulnerability to relapse, nor has abrupt nicotine dose reduction been evaluated in terms of behavioral economic characteristics of demand and elasticity been evaluated for reduced doses of nicotine. Using a rat model, we first evaluated the comparability of between- and within-session protocols for establishing characteristics of demand and elasticity for nicotine to shorten experimental timelines for this study ...

Contributors
Cabrera-Brown, Gabriella, Gipson-Reichardt, Cassandra, Olive, M. Foster, et al.
Created Date
2017-12-08

Exosomes have been known to secrete an increased amount of miRNA and noncoding genes that are abnormally expressed in various cancer subtypes. Thus, they may be an early marker for pediatric cancer types that are more difficult to diagnosis without invasive techniques, and may also help identify progression of the disease. In the project, six types of pediatric cancer cell lines, along with their extracted exosomes, were analyzed and tested for different monoclonal antibodies through western blot analysis. The genes EWS-FLI1 and FGFR4 were also identified in some cancer cell lines through Reverse-Transcriptase Polymerase Chain Reaction analysis (RT-PCR). The results ...

Contributors
Kaur Bhinder, Harsimran, Lake, Douglas, Azorsa, David
Created Date
2017-11-30

This thesis seeks to evaluate whether the benefits of spinal fusion surgeries are worth their increasing costs. The paper examines the trends that contribute to these surgeries’ increasing prices and then evaluates the customer impact of these surgeries in order to make a conclusion on whether the surgeries are worth it. This paper discusses the main factors that contribute to the increase in prices of these surgeries and these include the aging population, the increase in diabetes rates, and the practice of purchasing physicians owned distributorships (PODs) devices in some hospitals. The paper concluded that there is a definite correlation ...

Contributors
Disengi Nkunzi, Jossel, Allenby, Braden, Bohl, Michael
Created Date
2017-11-20

Coronaviruses are a significant group of viruses that cause enteric and respiratory infections in a variety of animals, including humans. Outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome (MERS) in the past 15 years has increased research into coronaviruses to gain an understanding of their structure and function so one day therapies and vaccines may be produced. These viruses have four main structural proteins: the spike, nucleocapsid, envelope, and membrane proteins. The envelope (E) protein is an integral membrane protein in the viral envelope that acts as a viroporin for transport of cations and plays an ...

Contributors
Haller, Sarah S., Hogue, Brenda, Liu, Wei, et al.
Created Date
2017-05

Identifying disease biomarkers may aid in the early detection of breast cancer and improve patient outcomes. Recent evidence suggests that tumors are immunogenic and therefore patients may launch an autoantibody response to tumor associated antigens. Single-chain variable fragments of autoantibodies derived from regional lymph node B cells of breast cancer patients were used to discover these tumor associated biomarkers on protein microarrays. Six candidate biomarkers were discovered from 22 heavy chain-only variable region antibody fragments screened. Validation tests are necessary to confirm the tumorgenicity of these antigens. However, the use of single-chain variable autoantibody fragments presents a novel platform for ...

Contributors
Sharman, M. Camila, Magee, Dewey, Wallstrom, Garrick, et al.
Created Date
2012-12

Hydrothermal Liquefaction of Algae represents one of many pathways for the sustainable replacement of fossil fuels in transportation. When processing and researching algal biofuel, determination of the higher heating value (HHV) is paramount. Bomb calorimetry represents to current method for direct determination of HHV. When determining HHV’s indirectly, the industry standard is using one of many linear correlations relating elemental composition to HHV. Most of these correlations were developed from coal industry data, meaning that they do not necessarily fit algal product data well. In this study bomb calorimetry data and CHNS/O elemental composition data were collected for Chlorella, Micract, ...

Contributors
Copp, Connor Joseph, Deng, Shuguang, Muppaneni, Tapaswy, et al.
Created Date
2017-05

The purpose of this study was to examine whether positive affirmations can lower depressive symptoms amongst male and female Arizona State University (ASU) honors students. Male and female ASU honors students (20-22 years of age; N=40) were recruited from Barrett, the Honors College, through email and online newsletters. Students who had been previously or were at the time diagnosed with clinical depression were not permitted to participate in the study. Only 9 female and 14 males completed the entire study. Participants completed a pre- and post- test that each consisting of reading aloud questions and their answers from the Beck’s ...

Contributors
Duran, Jose, Chan, Angie, Chisum, Jack, et al.

The purpose of this study was to examine whether positive affirmations can lower depressive symptoms amongst male and female Arizona State University (ASU) honors students. Male and female ASU honors students (20-22 years of age; N=40) were recruited from Barrett, the Honors College, through email and online newsletters. Students who had been previously or were at the time diagnosed with clinical depression were not permitted to participate in the study. Only 9 female and 14 males completed the entire study. Participants completed a pre- and post- test that each consisting of reading aloud questions and their answers from the Beck’s ...

Contributors
Chan, Angie, Duran, Jose, Chisum, Jack, et al.

This paper investigates the effect of government subsidies on the performance of new energy companies. An empirical analysis using data from Chinese A-share listed new energy firms and companies of other industries under standard classification of industries by China Securities and Regulatory Commission and a case study of GCL-Poly are combined. The result shows that government subsidies have negative effects on new energy companies' performance and their R&D intensity.

Contributors
Cao, Li

We were driven by the question: what is happening to the popularity of Major League Baseball? In order to answer this question we compared the league structure of Major League Baseball with that of the National Football League. We were able to speak with five former or current members of the respective leagues in order to gain some insight into how the two leagues operate. The main focus of our research was around the payroll structures of the two leagues as well as their revenue sharing policies. In the end, we discovered that Major League Baseball is becoming highly regionalized. ...

Contributors
Heath, Cameron, Linamen, John, Eaton, John, et al.
Created Date
2015-05

Barrett, the Honors College accepts high performing, academically engaged students and works with them in collaboration with all of the other academic units at Arizona State University. All Barrett students complete a thesis or creative project, supervised and defended in front of a faculty committee. The thesis or creative project allows students to explore an intellectual interest and produce an original piece of scholarly research. The thesis or creative project is a student’s opportunity to explore areas of academic interest with greater intensity than is possible in a single course. It is also an opportunity to engage with professors, nationally recognized in their fields and specifically interested and committed to working with honors students. This work provides tangible evidence of a student’s research, writing and creative skills to graduate schools and/or prospective employers.