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2014 2017

Many upper limb amputees experience an incessant, post-amputation “phantom limb pain” and report that their missing limbs feel paralyzed in an uncomfortable posture. One hypothesis is that efferent commands no longer generate expected afferent signals, such as proprioceptive feedback from changes in limb configuration, and that the mismatch of motor commands and visual feedback is interpreted as pain. Non-invasive therapeutic techniques for treating phantom limb pain, such as mirror visual feedback (MVF), rely on visualizations of postural changes. Advances in neural interfaces for artificial sensory feedback now make it possible to combine MVF with a high-tech “rubber hand” illusion, in ...

Contributors
Hellman, Randall, Chang, Eric, Tanner, Justin, et al.
Created Date
2015-02-19
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Agassiz’s desert tortoise (Gopherus agassizii) is a long-lived species native to the Mojave Desert and is listed as threatened under the US Endangered Species Act. To aid conservation efforts for preserving the genetic diversity of this species, we generated a whole genome reference sequence with an annotation based on deep transcriptome sequences of adult skeletal muscle, lung, brain, and blood. The draft genome assembly for G. agassizii has a scaffold N50 length of 252 kbp and a total length of 2.4 Gbp. Genome annotation reveals 20,172 protein-coding genes in the G. agassizii assembly, and that gene structure is more similar ...

Contributors
Tollis, Marc, DeNardo, Dale F, Cornelius, John A, et al.
Created Date
2017-05-31

Supply-demand processes take place on a large variety of real-world networked systems ranging from power grids and the internet to social networking and urban systems. In a modern infrastructure, supply-demand systems are constantly expanding, leading to constant increase in load requirement for resources and consequently, to problems such as low efficiency, resource scarcity, and partial system failures. Under certain conditions global catastrophe on the scale of the whole system can occur through the dynamical process of cascading failures. We investigate optimization and resilience of time-varying supply-demand systems by constructing network models of such systems, where resources are transported from the ...

Contributors
Zhang, Si-Ping, Huang, Zi-Gang, Dong, Jia-Qi, et al.
Created Date
2015-06-23

Stable salt-bridge network between Lys300 and Asp163/Asp164. The conformation of the network is essentially unchanged over the course of the whole simulation, and hence only the first 250 ns are shown. A sodium ion spontaneously binds to Asp133 and Asp164. Asp133 moves away, leaving the ion with Asp164. The salt bridge Lys300–Asp163 breaks and Asp163 binds the Na+ ion together with Asp164, preventing the reformation of the salt bridge. These interactions remain until the end of the 1-µs simulation, even though only the first 250 ns are shown.

Contributors
Lee, Chiara, Yashiro, Shoko, Dotson, David, et al.
Created Date
2014-12-01

This study investigates the impact of urban form and landscaping type on the mid-afternoon microclimate in semi-arid Phoenix, Arizona. The goal is to find effective urban form and design strategies to ameliorate temperatures during the summer months. We simulated near-ground air temperatures for typical residential neighborhoods in Phoenix using the three-dimensional microclimate model ENVI-met. The model was validated using weather observations from the North Desert Village (NDV) landscape experiment, located on the Arizona State University's Polytechnic campus. The NDV is an ideal site to determine the model's input parameters, since it is a controlled environment recreating three prevailing residential landscape ...

Contributors
Middel, Ariane, Hab, Kathrin, Brazel, Anthony J., et al.
Created Date
2014-02