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ASU Scholarship Showcase


This growing collection consists of scholarly works authored by ASU-affiliated faculty, students and community members, and contains many open access articles. ASU-affiliated authors are encouraged to Share Your Work in the ASU Digital Repository.


Date Range
2006 2019


There are an increasing variety of applications in which peptides are both synthesized and used attached to solid surfaces. This has created a need for high throughput sequence analysis directly on surfaces. However, common sequencing approaches that can be adapted to surface bound peptides lack the throughput often needed in library-based applications. Here we describe a simple approach for sequence analysis directly on solid surfaces that is both high speed and high throughput, utilizing equipment available in most protein analysis facilities. In this approach, surface bound peptides, selectively labeled at their N-termini with a positive charge-bearing group, are subjected to …

Contributors
Zhao, Zhan-Gong, Cordovez, Lalaine Anne, Johnston, Stephen, et al.
Created Date
2017-12-19

Starting with the dynamical picture of the exotic c[¯over c]-containing states XYZas the confinement-induced hadronization of a rapidly separating pair of a compact diquark and antidiquark, we describe the pentaquark candidates P[+ over c](4380)and P[+ over c](4450)in terms of a confined but rapidly separating color-antitriplet diquark cuand color-triplet “triquark” [¯ over c](ud). This separation explains the relatively small P[+ over c] widths, despite these 5-quark systems lying far above both the J/ψp and A[subscript c] [¯ over D][superscript (∗)0] thresholds. The P[+ over c] states are predicted to form isospin doublets with neutral partners P[0 over c].

Contributors
Lebed, Richard, College of Liberal Arts and Sciences, Department of Physics
Created Date
2015-08-17

Sustainable fisheries management is key to restoring and maintaining ecological function and benefits to people, but it requires accurate information about patterns of resource use, particularly fishing pressure. In most coral reef fisheries and other data-poor contexts, obtaining such information is challenging and remains an impediment to effective management. We developed the most comprehensive regional view of shore-based fishing effort and catch published to date, to show detailed fishing patterns from across the main Hawaiian Islands (MHI). We reveal these regional patterns through fisher “creel” surveys conducted by local communities, state agencies, academics, and/or environmental organizations, at 18 sites, comprising …

Contributors
Delaney, David G., Teneva, Lida T., Stamoulis, Kostantinos A., et al.
Created Date
2017-12-04

Public health messaging about antimicrobial resistance (AMR) sometimes conveys the problem as an epidemic. We outline why AMR is a serious endemic problem manifested in hospital and community-acquired infections. AMR is not an epidemic condition, but may complicate epidemics, which are characterised by sudden societal impact due to rapid rise in cases over a short timescale. Influenza, which causes direct viral effects, or secondary bacterial complications is the most likely cause of an epidemic or pandemic where AMR may be a problem. We discuss other possible causes of a pandemic with AMR, and present a risk assessment formula to estimate …

Contributors
MacIntyre, Chandini, Bui, Chau Minh, College of Public Service and Community Solutions
Created Date
2017-09-14

Delays are a major cause for concern in the construction industry in Saudi Arabia. This paper identifies the main causes of delay in infrastructure projects in Mecca, Saudi Arabia, and compares these with projects around the country and other Gulf countries. Data was obtained from 49 infrastructure projects undertaken by the owner and were analyzed quantitatively to understand the severity and causes of delay. 10 risk factors were identified and were grouped into four categories. Average delay in infrastructure projects in Mecca was found to be 39%. The most severe cause of delay was found to be the land acquisition …

Contributors
Elawi, Ghazi, Algahtany, Mohammed, Kashiwagi, Dean, et al.
Created Date
2016-05-20

Quantitative three-dimensional (3D) computed tomography (CT) imaging of living single cells enables orientation-independent morphometric analysis of the intricacies of cellular physiology. Since its invention, x-ray CT has become indispensable in the clinic for diagnostic and prognostic purposes due to its quantitative absorption-based imaging in true 3D that allows objects of interest to be viewed and measured from any orientation. However, x-ray CT has not been useful at the level of single cells because there is insufficient contrast to form an image. Recently, optical CT has been developed successfully for fixed cells, but this technology called Cell-CT is incompatible with live-cell …

Contributors
Kelbauskas, Laimonas, Shetty, Rishabh Manoj, Cao, Bin, et al.
Created Date
2017-12-06

With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits. Host immunity, tumor microenvironment and abnormal vascularity contribute to inefficient vector delivery. A number of novel approaches for enhanced OV delivery are under evaluation, including use of nanoparticles, immunomodulatory agents and complex viral–particle ligands along with manipulations of the tumor microenvironment. This field of OV delivery has quickly evolved to bioengineering of complex nanoparticles that could be deposited within the tumor using minimal invasive image-guided delivery. Some of the strategies include ultrasound (US)-mediated …

Contributors
Yokoda, Raquel, Nagalo, Bolni M., Vernon, Brent, et al.
Created Date
2017-11-08

Human physical interactions can be intrapersonal, e.g., manipulating an object bimanually, or interpersonal, e.g., transporting an object with another person. In both cases, one or two agents are required to coordinate their limbs to attain the task goal. We investigated the physical coordination of two hands during an object-balancing task performed either bimanually by one agent or jointly by two agents. The task consisted of a series of static (holding) and dynamic (moving) phases, initiated by auditory cues. We found that task performance of dyads was not affected by different pairings of dominant and non-dominant hands. However, the spatial configuration …

Contributors
Mojtahedi, Keivan, Fu, Qiushi, Santello, Marco, et al.
Created Date
2017-11-07

A general consensus on the concept of rainfall intermittency has not yet been reached, and intermittency is often attributed to different aspects of rainfall variability, including the fragmentation of the rainfall support (i.e., the alternation of wet and dry intervals) and the strength of intensity fluctuations and bursts. To explore these different aspects, a systematic analysis of rainfall intermittency properties in the time domain is presented using high-resolution (1-min) data recorded by a network of 201 tipping-bucket gauges covering the entire island of Sardinia (Italy). Four techniques, including spectral and scale invariance analysis, and computation of clustering and intermittency exponents, …

Contributors
Mascaro, Giuseppe, Deidda, R., Hellies, M., et al.
Created Date
2013-01-29

A semi-nonparametric generalized multinomial logit model, formulated using orthonormal Legendre polynomials to extend the standard Gumbel distribution, is presented in this paper. The resulting semi-nonparametric function can represent a probability density function for a large family of multimodal distributions. The model has a closed-form log-likelihood function that facilitates model estimation. The proposed method is applied to model commute mode choice among four alternatives (auto, transit, bicycle and walk) using travel behavior data from Argau, Switzerland. Comparisons between the multinomial logit model and the proposed semi-nonparametric model show that violations of the standard Gumbel distribution assumption lead to considerable inconsistency in …

Contributors
Wang, Ke, Ye, Xin, Pendyala, Ram, et al.
Created Date
2017-10-26