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ASU Electronic Theses and Dissertations


This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.

In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.

Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.


Date Range
2012 2019


Unstructured texts containing biomedical information from sources such as electronic health records, scientific literature, discussion forums, and social media offer an opportunity to extract information for a wide range of applications in biomedical informatics. Building scalable and efficient pipelines for natural language processing and extraction of biomedical information plays an important role in the implementation and adoption of applications in areas such as public health. Advancements in machine learning and deep learning techniques have enabled rapid development of such pipelines. This dissertation presents entity extraction pipelines for two public health applications: virus phylogeography and pharmacovigilance. For virus phylogeography, geographical locations …

Contributors
Magge, Arjun, Scotch, Matthew, Gonzalez-Hernandez, Graciela, et al.
Created Date
2019

The recent technological advances enable the collection of various complex, heterogeneous and high-dimensional data in biomedical domains. The increasing availability of the high-dimensional biomedical data creates the needs of new machine learning models for effective data analysis and knowledge discovery. This dissertation introduces several unsupervised and supervised methods to help understand the data, discover the patterns and improve the decision making. All the proposed methods can generalize to other industrial fields. The first topic of this dissertation focuses on the data clustering. Data clustering is often the first step for analyzing a dataset without the label information. Clustering high-dimensional data …

Contributors
Lin, Sangdi, Runger, George C, Kocher, Jean-Pierre A, et al.
Created Date
2018

Major Depression, clinically called Major Depressive Disorder, is a mood disorder that affects about one eighth of population in US and is projected to be the second leading cause of disability in the world by the year 2020. Recent advances in biotechnology have enabled us to collect a great variety of data which could potentially offer us a deeper understanding of the disorder as well as advancing personalized medicine. This dissertation focuses on developing methods for three different aspects of predictive analytics related to the disorder: automatic diagnosis, prognosis, and prediction of long-term treatment outcome. The data used for each …

Contributors
Nie, Zhi, Ye, Jieping, He, Jingrui, et al.
Created Date
2017

There has been tremendous technological advancement in the past two decades. Faster computers and improved sensing devices have broadened the research scope in computer vision. With these developments, the task of assessing the quality of human actions, is considered an important problem that needs to be tackled. Movement quality assessment finds wide range of application in motor control, health-care, rehabilitation and physical therapy. Home-based interactive physical therapy requires the ability to monitor, inform and assess the quality of everyday movements. Obtaining labeled data from trained therapists/experts is the main limitation, since it is both expensive and time consuming. Motivated by …

Contributors
Som, Anirudh, Turaga, Pavan, Krishnamurthi, Narayanan, et al.
Created Date
2016

No two cancers are alike. Cancer is a dynamic and heterogeneous disease, such heterogeneity arise among patients with the same cancer type, among cancer cells within the same individual’s tumor and even among cells within the same sub-clone over time. The recent application of next-generation sequencing and precision medicine techniques is the driving force to uncover the complexity of cancer and the best clinical practice. The core concept of precision medicine is to move away from crowd-based, best-for-most treatment and take individual variability into account when optimizing the prevention and treatment strategies. Next-generation sequencing is the method to sift through …

Contributors
Peng, Sen, Dinu, Valentin, Scotch, Matthew, et al.
Created Date
2015

Hospital Emergency Departments (EDs) are frequently crowded. The Center for Medicare and Medicaid Services (CMS) collects performance measurements from EDs such as that of the door to clinician time. The door to clinician time is the time at which a patient is first seen by a clinician. Current methods for documenting the door to clinician time are in written form and may contain inaccuracies. The goal of this thesis is to provide a method for automatic and accurate retrieval and documentation of the door to clinician time. To automatically collect door to clinician times, single board computers were installed in …

Contributors
Frisby, Joshua, Nelson, Brian C, Patel, Vimla L, et al.
Created Date
2015

When scientific software is written to specify processes, it takes the form of a workflow, and is often written in an ad-hoc manner in a dynamic programming language. There is a proliferation of legacy workflows implemented by non-expert programmers due to the accessibility of dynamic languages. Unfortunately, ad-hoc workflows lack a structured description as provided by specialized management systems, making ad-hoc workflow maintenance and reuse difficult, and motivating the need for analysis methods. The analysis of ad-hoc workflows using compiler techniques does not address dynamic languages - a program has so few constrains that its behavior cannot be predicted. In …

Contributors
Acuna, Ruben, Bazzi, Rida, Lacroix, Zoe, et al.
Created Date
2015

In blindness research, the corpus callosum (CC) is the most frequently studied sub-cortical structure, due to its important involvement in visual processing. While most callosal analyses from brain structural magnetic resonance images (MRI) are limited to the 2D mid-sagittal slice, we propose a novel framework to capture a complete set of 3D morphological differences in the corpus callosum between two groups of subjects. The CCs are segmented from whole brain T1-weighted MRI and modeled as 3D tetrahedral meshes. The callosal surface is divided into superior and inferior patches on which we compute a volumetric harmonic field by solving the Laplace's …

Contributors
Xu, Liang, Wang, Yalin, Maciejewski, Ross, et al.
Created Date
2013

Surgery as a profession requires significant training to improve both clinical decision making and psychomotor proficiency. In the medical knowledge domain, tools have been developed, validated, and accepted for evaluation of surgeons' competencies. However, assessment of the psychomotor skills still relies on the Halstedian model of apprenticeship, wherein surgeons are observed during residency for judgment of their skills. Although the value of this method of skills assessment cannot be ignored, novel methodologies of objective skills assessment need to be designed, developed, and evaluated that augment the traditional approach. Several sensor-based systems have been developed to measure a user's skill quantitatively, …

Contributors
Islam, Gazi, Li, Baoxin, Liang, Jianming, et al.
Created Date
2013

Biological systems are complex in many dimensions as endless transportation and communication networks all function simultaneously. Our ability to intervene within both healthy and diseased systems is tied directly to our ability to understand and model core functionality. The progress in increasingly accurate and thorough high-throughput measurement technologies has provided a deluge of data from which we may attempt to infer a representation of the true genetic regulatory system. A gene regulatory network model, if accurate enough, may allow us to perform hypothesis testing in the form of computational experiments. Of great importance to modeling accuracy is the acknowledgment of …

Contributors
Verdicchio, Michael Paul, Kim, Seungchan, Baral, Chitta, et al.
Created Date
2013