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ASU Electronic Theses and Dissertations


This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.

In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.

Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.




To date, there have not been any studies in a human population that explore the potential of vinegar ingestion in reducing visceral fat, a common yet serious metabolic disease risk factor. However, previous research in animal models exhibit promising findings, showing that vinegar is effective at reducing visceral fat. This is thought to be due to the activation of AMPK (adenosine monophosphate protein kinase) by acetic acid, the active ingredient in vinegar. The purpose of this study was to identify if this potentially groundbreaking relationship exists in human subjects. Healthy, nonsmoking, sedentary adults between the ages 18-45 y and a …

Contributors
Baker, Olivia Laurel, Johnston, Carol, Mayol-Kreiser, Sandra, et al.
Created Date
2018

ABSTRACT Many natural interventions have been effective at lowering postprandial glucose concentrations (PPG) in research trials and, theoretically, should have favorable effects on the prevention and management of T2DM. Natural interventions include vinegar, nuts and exercise. Green tea has been demonstrated to also possessing antiglycemic effects. Thus, green tea, and its most abundant catechin EGCG, are being consumed for its potential health benefits in cancer prevention and in its inhibitory effects on α-amylase. Many studies have found EGCG to inhibit α-amylase an enzyme needed in the breakdown of carbohydrates (CHO). Other studies have looked at EGCG and its potential for …

Contributors
Romash, Roni Genna, Johnston, Carol, Dixon, Kathleen, et al.
Created Date
2018

Curcumin is an active ingredient of Curcuma longa (Turmeric) and is studied extensively for its antioxidant, anti-inflammatory, anti-bacterial, anti-viral, and anti-cancer properties. The purpose of this study was to examine the effects of turmeric on blood glucose and plasma insulin levels. The study utilized a placebo-controlled, randomized cross-over design with participants serving as their own control. Eight glucose tolerant healthy participants completed the full study. Three-weeks washout period was kept in between six-weeks. Prior to the test meal day, participants were asked to eat a bagel with their evening dinner. During the day of the test meal, participants reported to …

Contributors
Oza, Namrata, Johnston, Carol, Mayol-Kreiser, Sandra, et al.
Created Date
2017

There are limited studies exploring the direct relationship between coconut oil and cholesterol concentrations. Research in animals and a few intervention trials suggest that coconut oil increases the good cholesterol (high density lipoprotein, HDL) and thus reduces the risk of cardiovascular disease. Preliminary research at Arizona State University (ASU) has found similar results using coconut oil as a placebo, positive changes in HDL cholesterol concentrations were observed. The goal of this randomized, double blind, parallel two arm study, was to further examine the beneficial effects of a 2g supplement of coconut oil taken each day for 8 weeks on cholesterol …

Contributors
Shedden, Rachel Nikita, Johnston, Carol, Lespron, Christy, et al.
Created Date
2017

Cardiovascular disease is the leading cause of death in the world, responsible for 17.3 million deaths annually. Aerobic activity and almond ingestion have a cardio-protective effect against cardiovascular disease, however, the synergistic effect of both interventions is not known. This 8-week randomized, parallel, two-arm study examined the combined effect of daily almond ingestion (2.5 ounces) and brisk walking (10,000 steps per day) compared to ingestion of an isocaloric placebo (4 Tbsp cookie butter) and brisk walking (10,000 steps per day) in sedentary adults on various markers of cardiovascular health. The additive effect of the daily walking intervention with almond consumption …

Contributors
Schwab, Emily, Sweazea, Karen, Johnston, Carol, et al.
Created Date
2017

Background: Acetic acid in vinegar has demonstrated antiglycemic effects in previous studies; however, the mechanism is unknown. Objective: To determine whether acetic acid dissociates in the addition of sodium chloride and describe a flavorful vinaigrette that maintains the functional properties of acetic acid. Design: Phase I - Ten healthy subjects (23-40 years) taste tested five homemade vinaigrette and five commercial dressings. Perceived saltiness, sweetness, tartness, and overall tasted were scored using a modified labeled affective magnitude scale. Each dressing was tested three times for pH with a calibrated meter. Phase II – Randomized crossover trial testing six dressings against a …

Contributors
Bonsall, Amber Kaila, Johnston, Carol, Mayol-Kreiser, Sandra, et al.
Created Date
2017

Birds have shown promise as models of diabetes due to health and longevity despite naturally high plasma glucose concentrations, a condition which in diabetic humans leads to protein glycation and various complications. Research into mechanisms that protect birds from high plasma glucose have shown that some species of birds have naturally low levels of protein glycation. Some hypothesize a diet rich in carotenoids and other antioxidants protects birds from protein glycation and oxidative damage. There is little research, however, into the amount of protein glycation in birds of prey, which consume a high protein, high fat diet. No studies have …

Contributors
Ingram, Tana Dawn, Sweazea, Karen, Johnston, Carol, et al.
Created Date
2017

Drinking vinegar is a popularly discussed remedy for relieving heartburn symptom, as can be read on many websites; however, there has been no scientific research or theory to support its efficacy. This randomized, placebo-controlled, double-blind, cross-over research study tested the efficacy of the organic apple cider vinegar, with mother, on alleviation of the heartburn symptom related to Gastro-esophageal reflux disease (GERD). A minimum of one week separated the four trial arms: chili (placebo), antacid after chili meal (positive control), vinegar added to chili, and diluted vinegar after chili meal. Twenty grams of vinegar were used in both vinegar treatments, and …

Contributors
Yeh, Zoe, Johnston, Carol, Mayol-Kreiser, Sandra, et al.
Created Date
2016

The glycation of plasma proteins leading to the production of advanced glycation end products (AGEs) and subsequent damage is a driving factor in the pathophysiology of diabetic complications. The overall research objective was to elucidate the mechanisms by which birds prevent protein glycation in the presence of naturally high plasma glucose concentrations. This was accomplished through the specific purpose of examining the impact of temperature and glucose concentration on the percent glycation of chicken serum albumin (CSA) in comparison to human serum albumin (HSA). Purified CSA and HSA solutions prepared at four different glucose concentrations (0 mM, 5.56 mM, 11.11 …

Contributors
Zuck, Jessica Ann, Sweazea, Karen, Johnston, Carol, et al.
Created Date
2016

Background: Individuals in the general populations with a known gluten disorder is believed to be 6% and it is unclear why the gluten free diet (GFD) has risen sharply (28%) in recent years. However, science has revealed that gluten can cause colonic changes in those undiagnosed with a known gluten disorder. The ramifications of these changes are unknown. Three common ingredients found in gluten free products, such as pasta, are corn quinoa and rice. Evidence from the scientific literature has shown that corn and quinoa can produce more colonic hydrogen than refined wheat and rice, indicating that corn and quinoa …

Contributors
Snyder, Darren Lawrence, Johnston, Carol, Ohri-Vachaspati, Punam, et al.
Created Date
2015