ASU Electronic Theses and Dissertations

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2004 2017

Telomerase is a special reverse transcriptase that extends the linear chromosome termini in eukaryotes. Telomerase is also a unique ribonucleoprotein complex which is composed of the protein component called Telomerase Reverse Transcriptase (TERT) and a telomerase RNA component (TR). The enzyme from most vertebrate species is able to utilize a short template sequence within TR to synthesize a long stretch of telomeric DNA, an ability termed "repeat addition processivity". By using human telomerase reconstituted both in vitro (Rabbit Reticulocyte Lysate) and in vivo (293FT cells), I have demonstrated that a conserved motif in the reverse transcriptase domain of the telomerase ...

Contributors
Xie, Mingyi, Chen, Julian J.L., Yan, Hao, et al.
Created Date
2010

Contemporary theories of trauma identify the creation of a coherent trauma narrative and therapeutic exposure to trauma memories as potential recovery mechanisms. These factors are often inherent to the disclosure process, resulting in a parallel theoretical framework for experimental research that conceptualizes disclosure as a therapeutic intervention. The present investigation examined the moderational impact of disclosure following trauma on the link between trauma severity and symptoms of Posttraumatic Stress Disorder (PTSD). Disclosure status (discloser or nondiscloser), highest extent of disclosure, and length of delay to first disclosure were tested in a series of moderated regression models among a sample of ...

Contributors
Fields, Briana, Barrera, Manuel, Holtfreter, Kristy, et al.
Created Date
2010

This thesis examines the modeling, analysis, and control system design issues for scramjet powered hypersonic vehicles. A nonlinear three degrees of freedom longitudinal model which includes aero-propulsion-elasticity effects was used for all analysis. This model is based upon classical compressible flow and Euler-Bernouli structural concepts. Higher fidelity computational fluid dynamics and finite elementmethods are needed formore precise intermediate and final evaluations. The methods presented within this thesis were shown to be useful for guiding initial control relevant design. The model was used to examine the vehicles static and dynamic characteristics over the vehicles trimmable region. The vehicle has significant longitudinal ...

Contributors
Korad, Akshay Shashikumar, Rodriguez, Armando A, Tsakalis, Konstantinos S, et al.
Created Date
2010

Since scholars first turned their attention to the subject some eighty years ago, one major area of contention in the study of Anglo-Saxon wills has been the function of the written will within Anglo-Saxon culture. Verbal agreements, formalized through oral ceremonies and symbolic actions, were recognized as legally binding; however, many of these agreements were also recorded in writing. Many scholars argue that the written document was superfluous;oral ceremonies were written down only in the case of memory failure and the documents themselves had no real performative function. Others see the existence of the written will to be evidence of ...

Contributors
Castle, Kasandra Marie, Bjork, Robert, Maring, Heather, et al.
Created Date
2010

"Globesity," as defined by the World Health Organization, describes obesity as a pandemic affecting at least 400 million people worldwide. The prevalence of obesity is higher among women than men; and in non-Hispanic black and Hispanic populations. Obesity has been significantly associated with increased all-cause mortality, and mortality from cardiovascular disease, obesity-related cancers, diabetes and kidney disease. Current strategies to curb obesity rates often use an ecological approach, suggesting three main factors: biological, behavioral, and environmental. This approach was used to develop four studies of obesity. The first study assessed dietary quality, using the Healthy Eating Index (HEI)-2005, among premenopausal ...

Contributors
Milliron, Brandy-Joe, Woolf, Kathleen, Vaughan, Linda, et al.
Created Date
2010

Prognostics and health management (PHM) is a method that permits the reliability of a system to be evaluated in its actual application conditions. This work involved developing a robust system to determine the advent of failure. Using the data from the PHM experiment, a model was developed to estimate the prognostic features and build a condition based system based on measured prognostics. To enable prognostics, a framework was developed to extract load parameters required for damage assessment from irregular time-load data. As a part of the methodology, a database engine was built to maintain and monitor the experimental data. This ...

Contributors
Varadarajan, Gayathri, Liu, Huan, Ye, Jieping, et al.
Created Date
2010

In a mere thirty years, hospice has grown from a purely ideological philosophy of care for terminally ill individuals and their families, to a large and well organized healthcare entity. And government statistics project that healthcare will generate more new jobs than any other industry in America until at least 2018. While most of the extant literature that has been published on healthcare workers has focused on negative organizational processes, such as stress and burnout, there has been a recent shift in scholarly ideology in which researchers have been challenged to consider the positive aspects of organizational life as well. ...

Contributors
Way, Deborah, Tracy, Sarah J, Carlson, Cheree, et al.
Created Date
2010

To establish reliable wireless communication links it is critical to devise schemes to mitigate the effects of the fading channel. In this regard, this dissertation analyzes two types of systems: point-to-point, and multiuser systems. For point-to-point systems with multiple antennas, switch and stay diversity combining offers a substantial complexity reduction for a modest loss in performance as compared to systems that implement selection diversity. For the first time, the design and performance of space-time coded multiple antenna systems that employ switch and stay combining at the receiver is considered. Novel switching algorithms are proposed and upper bounds on the pairwise ...

Contributors
Bangalore Narasimhamurthy, Adarsh, Tepedelenlioglu, Cihan, Duman, Tolga M, et al.
Created Date
2010

The music of Johann Sebastian Bach has long been used for keyboard percussion pedagogy and performance. The cello suites (BWV 1007-1012), in particular, are popular choices for marimbists. As with many transcriptions for marimba, performers are challenged to transfer Bach's musical genius onto an instrument whose timbre, range, mode of execution and acoustic properties are distinctly different from the original. To date, there is no concise and relevant edition of the suites for study and performance at the marimba. The edition contained herein solves most, if not all, of the problems normally confronted by marimbists. In addition to synthesizing the ...

Contributors
Sallak, William Leslie, Smith, J. B., Sunkett, Mark, et al.
Created Date
2010

The following study evaluated the effectiveness of a self-monitoring strategy on independent work behavior. The three subjects were in first grade, seven years old, identified with mild mental retardation (MIMR), and had an Individualized Education Plan (IEP) with targeted functional academic and behavior goals. The purpose of this study was to investigate the effect of a self-monitoring strategy on on-task independent work behavior and task completion. The research sought to determine whether or not a self-monitoring strategy would affect on-task independent work behavior and task completion. A multiple baseline across subjects design was used. Data were collected using a frequency ...

Contributors
Coughlin, Jennifer Henderson, Mccoy, Kathleen, Kenzer, Amy, et al.
Created Date
2010

This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.

In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.

Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries.

For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.