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Thermodynamics and Kinetics of DNA Nanostructure Assembly


Abstract ABSTRACT The unique structural features of deoxyribonucleic acid (DNA) that are of considerable biological interest also make it a valuable engineering material. Perhaps the most useful property of DNA for molecular engineering is its ability to self-assemble into predictable, double helical secondary structures. These interactions are exploited to design a variety of DNA nanostructures, which can be organized into both discrete and periodic structures. This dissertation focuses on studying the dynamic behavior of DNA nanostructure recognition processes. The thermodynamics and kinetics of nanostructure binding are evaluated, with the intention of improving our ability to understand and control their assembly. Presented here are a series of ... (more)
Created Date 2011
Contributor Nangreave, Jeanette Kim (Author) / Yan, Hao (Advisor) / Liu, Yan (Advisor) / Chen, Julian J.-L. (Committee member) / Seo, Dong Kyun (Committee member) / Arizona State University (Publisher)
Subject Chemistry / Nanoscience / Physical chemistry / Binding / DNA Nanotechnology / Kinetics / Thermodynamics
Type Doctoral Dissertation
Extent 217 pages
Language English
Copyright
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Note Ph.D. Chemistry 2011
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis