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Evaluation of Nanoporous Carbon Thin Films for Drug Loading and Controlled Release


Abstract Mesoporous materials that possess large surface area, tunable pore size, and ordered structures are attractive features for many applications such as adsorption, protein separation, enzyme encapsulation and drug delivery as these materials can be tailored to host different guest molecules. Films provide a model system to understand how the pore orientation impacts the potential for loading and release of selectively sized molecules. This research work aims to develop structure-property relationships to understand how pore size, geometry, and surface hydrophobicity influence the loading and release of drug molecules. In this study, the pore size is systematically varied by incorporating pore-swelling agent of polystyrene oligomers (hPS) to s... (more)
Created Date 2011
Contributor Labiano, Alpha Chavez (Author) / Vogt, Bryan (Advisor) / Rege, Kaushal (Committee member) / Dai, Lenore (Committee member) / Potta, Thrimoorthy (Committee member) / Arizona State University (Publisher)
Subject Chemical engineering / carbon / controlled release / drug delivery / films / nanoporous
Type Masters Thesis
Extent 101 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note M.S. Chemical Engineering 2011
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis