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Gold Nanorod-based Assemblies and Composites: Cancer Therapeutics, Sensors and Tissue Engineering Materials

Abstract Gold nanoparticles as potential diagnostic, therapeutic and sensing systems have a long history of use in medicine, and have expanded to a variety of applications. Gold nanoparticles are attractive in biological applications due to their unique optical, chemical and biological properties. Particularly, gold nanorods (GNRs) are increasingly used due to superior optical property in the near infrared (NIR) window. Light absorbed by the nanorod can be dissipated as heat efficiently or re-emitted by the particle. However, the limitations for clinical translation of gold nanorods include low yields, poor stability, depth-restricted imaging, and resistance of cancer cells to hyperthermia, are severe. A novel high-throughput synthesis method was em... (more)
Created Date 2012
Contributor Huang, Huang-Chiao (Author) / Rege, Kaushal (Advisor) / Sierks, Michael (Committee member) / Dai, Lenore (Committee member) / Ramakrishna, B (Committee member) / Vogt, Bryan (Committee member) / Arizona State University (Publisher)
Subject Chemical engineering / Biomedical engineering / Combination treatment / Elastin-like Polypeptide / Gene delivery / Gold nanorod / Laser tissue welding / Photothermal therapy
Type Doctoral Dissertation
Extent 250 pages
Language English
Reuse Permissions All Rights Reserved
Note Ph.D. Chemical Engineering 2012
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis