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Experimental and Computational Assessment of Locomotor Coordination and Complexity Following Incomplete Spinal Cord Injury in the Rat


Abstract Spinal cord injury (SCI) disrupts the communication between supraspinal circuits and spinal circuits distal to the injury. This disruption causes changes in the motor abilities of the affected individual, but it can also be used as an opportunity to study motor control in the absence or limited presence of control from the brain. In the case of incomplete paraplegia, locomotion is impaired and often results in increased incidence of foot drag and decreased postural stability after injury. The overall goal of this work is to understand how changes in kinematics of movement and neural control of muscles effect locomotor coordination following SCI. Toward this end, we examined musculoskeletal parameters and kinematics of gait in rats with and ... (more)
Created Date 2012
Contributor Hillen, Brian (Author) / Jung, Ranu (Advisor) / Abbas, James (Committee member) / Muthuswamy, Jit (Committee member) / Jindrich, Devin (Committee member) / Yamaguchi, Gary (Committee member) / Arizona State University (Publisher)
Subject Biomedical engineering / Biomechanics / Neurosciences / computational / locomotion / rat / spinal cord injury
Type Doctoral Dissertation
Extent 138 pages
Language English
Copyright
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Note Ph.D. Bioengineering 2012
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis