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Advancing the lizard, Anolis carolinensis, as a model system for genomic studies of evolution, development and regeneration.


Abstract Well-established model systems exist in four out of the seven major classes of vertebrates. These include the mouse, chicken, frog and zebrafish. Noticeably missing from this list is a reptilian model organism for comparative studies between the vertebrates and for studies of biological processes unique to reptiles. To help fill in this gap the green anole lizard, Anolis carolinensis, is being adapted as a model organism. Despite the recent release of the complete genomic sequence of the A. carolinensis, the lizard lacks some resources to aid researchers in their studies. Particularly, the lack of transcriptomic resources for lizard has made it difficult to identify genes complete with alternative splice forms and untranslated regions (UTRs... (more)
Created Date 2012
Contributor Eckalbar, Walter (Author) / Kusumi, Kenro (Advisor) / Huentelman, Matthew (Committee member) / Rawls, Jeffery (Committee member) / Wilson-Rawls, Norma (Committee member) / Arizona State University (Publisher)
Subject Genetics / Developmental biology / Molecular biology / Development / Evolution / Genomics / Lizard / Regeneration / RNA-seq
Type Doctoral Dissertation
Extent 166 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note Ph.D. Molecular and Cellular Biology 2012
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis
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