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Improvement Strategies for the Production of Renewable Chemicals by Synechocystis sp PCC 6803


Abstract Synechocystis sp PCC 6803 is a photosynthetic cyanobacterium that can be easily transformed to produce molecules of interest; this has increased Synechocystis’ popularity as a clean energy platform. Synechocystis has been shown to produce and excrete molecules such as fatty acids, isoprene, etc. after appropriate genetic modification. Challenges faced for large–scale growth of modified Synechocystis include abiotic stress, microbial contamination and high processing costs of product and cell material. Research reported in this dissertation contributes to solutions to these challenges. First, abiotic stress was addressed by overexpression of the heat shock protein ClpB1. In contrast to the wild type, the ClpB1 overexpress... (more)
Created Date 2013
Contributor Gonzalez Esquer, Cesar Raul (Author) / Vermaas, Willem (Advisor) / Chandler, Douglas (Committee member) / Bingham, Scott (Committee member) / Nielsen, David (Committee member) / Arizona State University (Publisher)
Subject Molecular biology / Microbiology / Genetics / Biofuel / Heat Shock / Isoprene / Liquid-liquid extraction
Type Doctoral Dissertation
Extent 119 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note Ph.D. Plant Biology 2013
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis