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Representing, Reasoning and Answering Questions about Biological Pathways Various Applications


Abstract Biological organisms are made up of cells containing numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted, manifesting as disease symptoms. Thus, understanding these biochemical processes and their interrelationships is a primary task in biomedical research and a prerequisite for activities including diagnosing diseases and drug development. Scientists studying these interconnected processes have identified various pathways involved in drug metabolism, diseases, and signal transduction, etc. High-throughput technologies, new algorithms and speed improvements over the last decade have resulted in deeper knowledge about biological systems, leading to more refined pathways. Suc... (more)
Created Date 2014
Contributor Anwar, Saadat (Author) / Baral, Chitta (Advisor) / Inoue, Katsumi (Committee member) / Chen, Yi (Committee member) / Davulcu, Hasan (Committee member) / Lee, Joohyung (Committee member) / Arizona State University (Publisher)
Subject Computer science / Artificial intelligence / biological pathways / knowledge representation / question answering / reasoning
Type Doctoral Dissertation
Extent 401 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note Ph.D. Computer Science 2014
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis