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Thermodynamics and Biological Applications of DNA Nanostructures

Abstract DNA nanotechnology is one of the most flourishing interdisciplinary research fields. Through the features of programmability and predictability, DNA nanostructures can be designed to self-assemble into a variety of periodic or aperiodic patterns of different shapes and length scales, and more importantly, they can be used as scaffolds for organizing other nanoparticles, proteins and chemical groups. By leveraging these molecules, DNA nanostructures can be used to direct the organization of complex bio-inspired materials that may serve as smart drug delivery systems and in vitro or in vivo bio-molecular computing and diagnostic devices. In this dissertation I describe a systematic study of the thermodynamic properties of complex DNA nanostru... (more)
Created Date 2014
Contributor Wei, Xixi (Author) / Liu, Yan (Advisor) / Yan, Hao (Advisor) / Chen, Julian (Committee member) / Gould, Ian (Committee member) / Arizona State University (Publisher)
Subject Chemistry / Biochemistry / Applications / DNA nanostructures / Thermodynamics
Type Doctoral Dissertation
Extent 246 pages
Language English
Reuse Permissions All Rights Reserved
Note Ph.D. Chemistry 2014
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis