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Application of Recognition Tunneling in Single Molecule Identification

Abstract Single molecule identification is one essential application area of nanotechnology. The application areas including DNA sequencing, peptide sequencing, early disease detection and other industrial applications such as quantitative and quantitative analysis of impurities, etc. The recognition tunneling technique we have developed shows that after functionalization of the probe and substrate of a conventional Scanning Tunneling Microscope with recognition molecules ("tethered molecule-pair" configuration), analyte molecules trapped in the gap that is formed by probe and substrate will bond with the reagent molecules. The stochastic bond formation/breakage fluctuations give insight into the nature of the intermolecular bonding at a s... (more)
Created Date 2014
Contributor Zhao, Yanan (Author) / Lindsay, Stuart (Advisor) / Nemanich, Robert (Committee member) / Qing, Quan (Committee member) / Ros, Robert (Committee member) / Zhang, Peiming (Committee member) / Arizona State University (Publisher)
Subject Physics / Biophysics / Identification / Molecule / Recognition / Single / tunneling
Type Doctoral Dissertation
Extent 178 pages
Language English
Reuse Permissions All Rights Reserved
Note Ph.D. Physics 2014
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis