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Calcium-Mediated Excitation and Plasticity in Primary Olfactory Pathways of the Honey Bee Antennal Lobe

Abstract Spatiotemporal processing in the mammalian olfactory bulb (OB), and its analog, the invertebrate antennal lobe (AL), is subject to plasticity driven by biogenic amines. I study plasticity using honey bees, which have been extensively studied with respect to nonassociative and associative based olfactory learning and memory. Octopamine (OA) release in the AL is the functional analog to epinephrine in the OB. Blockade of OA receptors in the AL blocks plasticity induced changes in behavior. I have now begun to test specific hypotheses related to how this biogenic amine might be involved in plasticity in neural circuits within the AL. OA acts via different receptor subtypes, AmOA1, which gates calcium release from intracellular stores, and AmOA... (more)
Created Date 2014
Contributor Protas, Danielle Tatiana (Author) / Smith, Brian H (Advisor) / Neisewander, Janet (Committee member) / Anderson, Trent (Committee member) / Tyler, William (Committee member) / Vu, Eric (Committee member) / Arizona State University (Publisher)
Subject Neurosciences / Antennal Lobe / Apis mellifera / Biogenic amines / Olfaction / Plasticity / Projection neurons
Type Doctoral Dissertation
Extent 119 pages
Language English
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Neuroscience 2014
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis