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The Effect of Vitamin C Supplementation on sICAM-1 in Asthmatic Study Participants

Abstract The common cold is a significant cause of morbidity world-wide, with human rhinovirus infections accounting for a majority colds suffered each year. While the symptoms of the common cold are generally mild and self-limiting, vulnerable populations such as individuals with asthma can experience severe secondary complications including acute asthma exacerbation which can result in severe morbidity. Most human rhinovirus types utilize Intercellular Adhesion Molecule-1 (ICAM-1) as a receptor to enter cells and initiate infection. Expression of this cell-surface protein is elevated in the respiratory tract of asthma patients. The theoretical basis for this research is the observation that plasma measures of the soluble form of Intercellular ... (more)
Created Date 2014
Contributor Gnant, Lindsay (Author) / Johnston, Carol (Advisor) / Sweazea, Karen (Committee member) / Chang, Yung (Committee member) / Arizona State University (Publisher)
Subject Nutrition / Health sciences / Asthma / Common Cold / ICAM-1 / Rhinovirus / Vitamin C
Type Masters Thesis
Extent 94 pages
Language English
Reuse Permissions All Rights Reserved
Note Masters Thesis Nutrition 2014
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis