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Self-Assembly of Complex DNA Nanostructures and Reconfigurable DNA Devices


Abstract Deoxyribonucleic acid (DNA) has emerged as an excellent molecular building block for nanoconstruction in addition to its biological role of preserving genetic information. Its unique features such as predictable conformation and programmable intra- and inter-molecular Watson-Crick base pairing interactions make it a remarkable engineering material. A variety of convenient design rules and reliable assembly methods have been developed to engineer DNA nanostructures. The ability to create designer DNA architectures with accurate spatial control has allowed researchers to explore novel applications in directed material assembly, structural biology, biocatalysis, DNA

computing, nano-robotics, disease diagnosis, and drug delivery.

This dissert... (more)
Created Date 2015
Contributor Zhang, Fei (Author) / Yan, Hao (Advisor) / Liu, Yan (Advisor) / Gould, Ian (Committee member) / Zhang, Peiming (Committee member) / Arizona State University (Publisher)
Subject Chemistry / Engineering / Biochemistry
Type Doctoral Dissertation
Extent 338 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Chemistry 2015
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis