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Iron depletion therapy and chromium supplementation for improving insulin

Abstract The effects of iron and chromium blood concentrations have been linked to blood glucose control in diabetics. It is suggested that iron causes oxidative stress in the beta cells of the pancreas and adipocytes creating insulin insufficiency and resistance. Chromium is believed to increase the action of insulin through its biologically active molecule chromodulin. Both of these mechanisms are not clear. This 20 week case study tests the feasibility of combining iron depletion therapy followed by chromium supplementation to improve insulin sensitivity. This single case study followed a protocol of two blood donations separated by eight weeks followed by chromium supplementation of 250 µg of chromium picolinate once a day four weeks after ... (more)
Created Date 2015
Contributor Jarrett, Nia M. (Author) / Johnston, Carol (Advisor) / Lespron, Christy (Committee member) / Mayol-Kreiser, Sandra (Committee member) / Arizona State University (Publisher)
Subject Health sciences / Nutrition / Pathology / Blood Donations / Chromium / Diabetes / Iron / Phlebotomy / Supplementation
Type Masters Thesis
Extent 61 pages
Language English
Reuse Permissions All Rights Reserved
Note Masters Thesis Nutrition 2015
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis