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Potential Therapeutic Benefits of Flaxseeds in the Treatment of Type 2 Diabetes Symptoms

Abstract Background: Despite the reported improvements in glucose regulation associated with flaxseeds (Linum usitatissimum) few clinical trials have been conducted in diabetic participants. Objective: To evaluate the efficacy of ground flaxseed consumption at attenuating hyperglycemia, dyslipidemia, inflammation, and oxidative stress as compared to a control in adults with non-insulin dependent type 2 diabetes (T2D). Design: In a randomized parallel arm controlled efficacy trial, participants were asked to consume either 28 g/d ground flaxseed or the fiber-matched control (9 g/d ground psyllium husk) for 8 weeks. The study included 17 adults (9 male, 8 females; 46±14 y; BMI: 31.4±5.7 kg/m2) with a diagnosis of T2D ≥ 6 months. Main outcomes measured... (more)
Created Date 2015
Contributor Ricklefs, Kristin (Author) / Sweazea, Karen L (Advisor) / Johnston, Carol S (Committee member) / Gaesser, Glenn (Committee member) / Vega-López, Sonia (Committee member) / Gonzales, Rayna (Committee member) / Arizona State University (Publisher)
Subject Nutrition / Physiology / Health sciences / Diabetes / Flaxseeds / glucose regulation / inflammation / Nutrition / psyllium
Type Doctoral Dissertation
Extent 202 pages
Language English
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Nutrition 2015
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis