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Unearthing the Antibacterial Activity of a Natural Clay Deposit

Abstract The discovery and development of novel antibacterial agents is essential to address the rising health concern over antibiotic resistant bacteria. This research investigated the antibacterial activity of a natural clay deposit near Crater Lake, Oregon, that is effective at killing antibiotic resistant human pathogens. The primary rock types in the deposit are andesitic pyroclastic materials, which have been hydrothermally altered into argillic clay zones. High-sulfidation (acidic) alteration produced clay zones with elevated pyrite (18%), illite-smectite (I-S) (70% illite), elemental sulfur, kaolinite and carbonates. Low-sulfidation alteration at neutral pH generated clay zones with lower pyrite concentrations pyrite (4-6%), the mixed-layere... (more)
Created Date 2015
Contributor Morrison, Keith David (Author) / Williams, Lynda B (Advisor) / Williams, Stanley N (Advisor) / Misra, Rajeev (Committee member) / Shock, Everett (Committee member) / Anbar, Ariel (Committee member) / Arizona State University (Publisher)
Subject Biogeochemistry / Mineralogy / Microbiology / Antibacterial / Clay Minerals / Metal Speciation / Pathogens / Pyrite / Reactive Oxygen Species
Type Doctoral Dissertation
Extent 179 pages
Language English
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Geological Sciences 2015
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis