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A History of Cellular Senescence and Its Relation to Stem Cells in the Twentieth and Twenty-First Centuries


Abstract Researchers in the twentieth and twenty-first centuries identify the study of the intrinsic and external factors that influence human aging as senescence. A commonly held belief in the year 2015 is that at least some kinds of cells can replicate over long periods or even indefinitely, thereby meaning the cell does not undergo senescence (also known as replicative senescence) and is considered immortal. This study aims to provide information to answer the following question: While some scientists claim they can indefinitely culture a stem cell line in vitro, what are the consequences of those culturing practices? An analysis of a cluster of articles from the Embryo Project Encyclopedia provides information to suggest possible solutions to so... (more)
Created Date 2015
Contributor Bartlett, Zane N. (Author) / Maienschein, Jane (Advisor) / Ellison, Karin (Committee member) / Hurlbut, James (Committee member) / Arizona State University (Publisher)
Subject Biology / History / Cellular biology / aging / human embryonic stem cells / immortal cell lines / immortal cells / senescence / stem cells
Type Masters Thesis
Extent 128 pages
Language English
Note Masters Thesis Biology 2015
Collaborating Institutions ASU Graduate College / ASU Libraries
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis