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Microbiome After Bariatric Surgery and Microbial Insights into Surgical Weight Loss

Abstract Obesity is a worldwide epidemic accompanied by multiple comorbidities. Bariatric surgery is currently the most efficient treatment for morbid obesity and its comorbidities. The etiology of obesity is unknown, although genetic, environmental, and most recently, microbiome elements have been recognized as contributors to this rising epidemic. The role of the gut microbiome in weight-loss or weight-gain warrants investigation, and bariatric surgery provides a good model to study influences of the microbiome on host metabolism. The underlying goals of my research were to analyze (i) the factors that change the microbiome after bariatric surgery, (ii) the effects of different types of bariatric surgeries on the gut microbiome and metabolism,... (more)
Created Date 2016
Contributor Ilhan, Zehra Esra (Author) / Krajmalnik-Brown, Rosa (Advisor) / DiBaise, John K (Committee member) / Cadillo-Quiroz, Hinsby (Committee member) / Rittmann, Bruce E (Committee member) / Arizona State University (Publisher)
Subject Microbiology / Ecology / 16S rRNA gene sequencing / bariatric surgery / gut microbiome / metabolomics / microbial ecology
Type Doctoral Dissertation
Extent 220 pages
Language English
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Microbiology 2016
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis