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A Low-Cost Genomic Sensor for Ocean-Observing Systems and Infectious Disease Detection

Abstract Many environmental microorganisms such as marine microbes are un-culturable; hence, they should be analyzed in situ. Even though a few in situ ocean observing instruments have been available to oceanographers, their applications are limited, because these instruments are expensive and power hungry.

In this dissertation project, an inexpensive, portable, low-energy consuming, and highly quantitative microbiological genomic sensor has been developed for in situ ocean-observing systems. A novel real-time colorimetric loop-mediated isothermal amplification (LAMP) technology has been developed for quantitative detection of microbial nucleic acids. This technology was implemented on a chip-level device with an embedded inexpensive imaging device... (more)
Created Date 2017
Contributor Ci, Shufang (Author) / Meldrum, Deirdre R (Advisor) / Chao, Shih-hui (Committee member) / Neuer, Susanne (Committee member) / Arizona State University (Publisher)
Subject Engineering
Type Doctoral Dissertation
Extent 149 pages
Language English
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Biological Design 2017
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis