Skip to main content

A Hands-On Activity to Demonstrate the Central Dogma of Molecular Biology Via a Simulated VDJ Recombination Activity


Abstract Essential or enduring understandings are often defined as the underlying core concepts or “big ideas” we’d like our students to remember when much of the course content has been forgotten. The central dogma of molecular biology and how cellular information is stored, used, and conveyed is one of the essential understandings students should retain after a course or unit in molecular biology or genetics. An additional enduring understanding is the relationships between DNA sequence, RNA sequence, mRNA production and processing, and the resulting polypeptide/protein product. A final big idea in molecular biology is the relationship between DNA mutation and polypeptide change. To engage students in these essential understandings in a Genetics c... (more)
Created Date 2017-08-11
Contributor Marshall, Pamela (ASU author) / New College of Interdisciplinary Arts and Sciences / School of Mathematical and Natural Sciences
Series JOURNAL OF MICROBIOLOGY AND BIOLOGY EDUCATION
Type Text
Extent 4 pages
Language English
Identifier DOI: 10.1128/jmbe.v18i2.1277 / ISSN: 1935-7877 / ISSN: 1935-7885
Copyright
Reuse Permissions
Citation Marshall, P. A. (2017). A Hands-On Activity to Demonstrate the Central Dogma of Molecular Biology Via a Simulated VDJ Recombination Activity. Journal of Microbiology and Biology Education, 18(2). doi:10.1128/jmbe.v18i2.1277
Note The final version of this article, as published in Journal of Microbiology and Biology Education, can be viewed online at: http://www.asmscience.org/content/journal/jmbe/10.1128/jmbe.v18i2.1277
Collaborating Institutions ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


  Hands-On Activity to Demonstrate_2017.pdf
946.7 KB application/pdf
Download Count: 360