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Thermodynamic Modeling of Lipid Adaptation in Thermophilic Microbes


Abstract Lipids perform functions essential to life and have a variety of structures that are influenced by the organisms and environments that produced them. Lipids tend to resist degradation after cell death, leading to their widespread use as biomarkers in geobiology, though their interpretation is often tricky. Many lipid structures are shared among organisms and function in many geochemical conditions and extremes. I argue it is useful to interpret lipid distributions as a balance of functional necessity and energy cost. This work utilizes a quantitative thermodynamic framework for interpreting energetically driven adaptation in lipids.

Yellowstone National Park is a prime location to study biological adaptations to a wide range of temperature... (more)
Created Date 2018
Contributor Boyer, Grayson Maxwell (Author) / Shock, Everett (Advisor) / Hartnett, Hilairy (Committee member) / Herckes, Pierre (Committee member) / Arizona State University (Publisher)
Subject Biochemistry / Biogeochemistry
Type Doctoral Dissertation
Extent 214 pages
Language English
Copyright
Reuse Permissions All Rights Reserved
Note Doctoral Dissertation Chemistry 2018
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis