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Biochemical Networks Across Planets and Scales

Abstract Biochemical reactions underlie all living processes. Their complex web of interactions is difficult to fully capture and quantify with simple mathematical objects. Applying network science to biology has advanced our understanding of the metabolisms of individual organisms and the organization of ecosystems, but has scarcely been applied to life at a planetary scale. To characterize planetary-scale biochemistry, I constructed biochemical networks using global databases of annotated genomes and metagenomes, and biochemical reactions. I uncover scaling laws governing biochemical diversity and network structure shared across levels of organization from individuals to ecosystems, to the biosphere as a whole. Comparing real biochemical reaction ... (more)
Created Date 2018
Contributor Smith, Harrison Brodsky (Author) / Walker, Sara I (Advisor) / Anbar, Ariel D (Committee member) / Line, Michael R (Committee member) / Okie, Jordan G (Committee member) / Romaniello, Stephen J (Committee member) / Arizona State University (Publisher)
Subject Bioinformatics / Biochemistry / Planetology / Astrobiology / Organization of life / Physics of living systems / Structure of biology
Type Doctoral Dissertation
Extent 150 pages
Language English
Note Doctoral Dissertation Geological Sciences 2018
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis