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Autonomous MEMS- Based Intracellular Neural Interfaces


Abstract Intracellular voltage recordings from single neurons in vitro and in vivo have been fundamental to our understanding of neuronal function. Conventional electrodes and associated positioning systems for intracellular recording in vivo are large and bulky, which has largely restricted their use to single-channel recording from anesthetized animals. Further, intracellular recordings are very cumbersome, requiring a high degree of skill not readily achieved in a typical laboratory. This dissertation presents a robotic, head-mountable, MEMS (Micro-Electro-Mechanical Systems) based intracellular recording system to overcome the above limitations associated with form-factor, scalability and highly skilled and tedious manual operations required for... (more)
Created Date 2018
Contributor Sampath Kumar, Swathy (Author) / Muthuswamy, Jit (Advisor) / Abbas, James (Committee member) / Hamm, Thomas (Committee member) / Christen, Jennifer Blain (Committee member) / Buneo, Christopher (Committee member) / Arizona State University (Publisher)
Subject Bioengineering / brain implant / intracellular recording / microactuator / microelectrode array / neural recording / robot
Type Doctoral Dissertation
Extent 118 pages
Language English
Copyright
Note Doctoral Dissertation Biomedical Engineering 2018
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis