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Modulation of the Endogenous Cannabinoid System as a Therapeutic Target in the Treatment of Mental Health Disorders

Abstract Development of effective therapeutic interventions for the treatment of mental health disorders has been a significant driving force in the search to understand the human brain. Current treatments for mental health disorders rely on modulating neurotransmitter systems such as norepinephrine (NE), serotonin (5-HT), dopamine (DA) and γ-aminobutyric acid (GABA) to achieve clinically relevant relief of symptoms. While many medications are available to the clinician that individually target these neural systems, treatment often results in patients reporting unwanted side effects or experiencing incomplete relief. To counter this lack of treatment efficacy, further investigation of other avenues for achieving similar or better outcomes and pote... (more)
Created Date 2019
Contributor Stratton, Harrison James (Author) / Shafer, Michael (Advisor) / Olive, Micahel F (Advisor) / Wu, Jie (Committee member) / Arizona State University (Publisher)
Subject Neurosciences / Pharmacology / Health sciences / Anxiety / Cannabinoid / CB2 / Depression / Mental Health / Treatment
Type Masters Thesis
Extent 49 pages
Language English
Note Masters Thesis Biology 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis