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Analyzing Cellular Properties with Dielectrophoresis

Abstract Dielectrophoresis (DEP) is a technique that influences the motion of polarizable particles in an electric field gradient. DEP can be combined with other effects that influence the motion of a particle in a microchannel, such as electrophoresis and electroosmosis. Together, these three can be used to probe properties of an analyte, including charge, conductivity, and zeta potential. DEP shows promise as a high-resolution differentiation and separation method, with the ability to distinguish between subtly-different populations. This, combined with the fast (on the order of minutes) analysis times offered by the technique, lend it many of the features necessary to be used in rapid diagnostics and point-of-care devices.

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Created Date 2019
Contributor Hilton, Shannon (Author) / Hayes, Mark A (Advisor) / Borges, Chad (Committee member) / Herckes, Pierre (Committee member) / Arizona State University (Publisher)
Subject Analytical chemistry / Chemistry / Biophysics / antimicrobial resistance / bacterial analysis / diagnostics / dielectrophoresis / microfluidics / separations
Type Doctoral Dissertation
Extent 186 pages
Language English
Note Doctoral Dissertation Chemistry 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis