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Statistical Investigations of Parameters that Drive High-Shear Granulation


Abstract Granulation is a process within particle technology where a liquid binding agent is added to a powder bed to create larger granules to modify bulk properties for easier processing. Three sets of experiments were conducted to screen for which factors had the greatest effect on granule formation, size distribution, and morphological properties when wet granulating microcrystalline cellulose and water. Previous experiments had identified the different growth regimes within wet granulation, as well as the granule formation mechanisms in single-drop granulation experiments, but little research has been conducted to determine how results extracted from single drop experiments could be used to better understand the first principles that drive hi... (more)
Created Date 2019
Contributor Lay, Michael (Author) / Emady, Heather (Advisor) / Muhich, Christopher (Committee member) / Holloway, Julianne (Committee member) / Arizona State University (Publisher)
Subject Chemical engineering
Type Masters Thesis
Extent 69 pages
Language English
Copyright
Note Masters Thesis Chemical Engineering 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis