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The Effects of Acute Aerobic and Resistance Exercise on mTOR Signaling and Autophagy in Human Skeletal Muscle


Abstract Exercise serves as a powerful stimulus to induce skeletal muscle adaptation. For instance, it is well understood that aerobic exercise (AE) elicits an adaptive response ultimately leading to increased fatigue resistance and capillarization, whereas resistance exercise (RE) is known to elicit an adaptive response leading to increased muscle strength and size. However, the precise molecular mechanisms mediating these unique adaptations to different forms of exercise remain to be completely resolved. The purpose of this study was to investigate the adaptive cellular response of skeletal muscle following acute AE and RE. Specifically, this study focused on two molecular processes: 1) mammalian/mechanistic target of rapamycin (mTOR) signaling pa... (more)
Created Date 2019
Contributor Mazo, Corey (Author) / Dickinson, Jared M (Advisor) / Carroll, Chad C (Committee member) / Angadi, Siddartha S (Committee member) / Arizona State University (Publisher)
Subject Health sciences
Type Masters Thesis
Extent 75 pages
Language English
Copyright
Note Masters Thesis Exercise and Wellness 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis