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The Characterization of Cannabidiol Amorphous Solid Dispersions


Abstract Generating amorphous solid dispersions (ASDs) containing active pharmaceutical ingredients has become a favorable technique of emerging prominence to improve drug solubility and overall bioavailability. Cannabidiol (CBD) has now become a major focus in cannabinoid research due to its ability to serve as an anti-inflammatory agent, showing promising results in treating a wide array of debilitating diseases and pathologies. The following work provides evidence for generating homogenous glass phase amorphous solid dispersions containing 50% (w/w) up to 75% (w/w) CBD concentrations in the domain size of 2 – 5 nm. Concentrations up to 85% (w/w) CBD were concluded homogenous in the supercooled liquid phase in domain sizes of 20 – 30 nm. The resul... (more)
Created Date 2019
Contributor Blass, Brandon Lewis (Author) / Yarger, Jeff L (Advisor) / Holland, Greg (Committee member) / Moore, Gary (Committee member) / Arizona State University (Publisher)
Subject Biochemistry
Type Masters Thesis
Extent 44 pages
Language English
Copyright
Note Masters Thesis Biochemistry 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis