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Acute Vagus Nerve Stimulation Spares Motor Map Topography and Reduces Infarct Size After Cortical Ischemia


Abstract Stroke remains a leading cause of adult disability in the United States. In recent studies, chronic vagus nerve stimulation (VNS) has been proven to enhance functional recovery when paired with motor rehabilitation training after stroke. Other studies have also demonstrated that delivering VNS during the onset of a stroke may elicit some neuroprotective effects as observed in remaining neural tissue and motor function. While these studies have demonstrated the benefits of VNS as a treatment or therapy in combatting stroke damage, the mechanisms responsible for these effects are still not well understood or known. The aim of this research was to further investigate the mechanisms underlying the efficacy of acute VNS treatment of stroke b... (more)
Created Date 2019
Contributor Okada, Kristen Yuri (Author) / Kleim, Jeffrey A (Advisor) / Si, Jennie (Advisor) / Helms Tillery, Stephen (Committee member) / Arizona State University (Publisher)
Subject Neurosciences / Biomedical engineering / Ischemia / Stroke / Vagus Nerve Stimulation
Type Masters Thesis
Extent 28 pages
Language English
Copyright
Note Masters Thesis Electrical Engineering 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis