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Eradication of Multidrug- Resistant Bacteria using Biomolecule-encapsulated Two-dimensional Materials


Abstract The increasing pervasiveness of infections caused by multidrug-resistant bacteria (MDR) is a major global health issue that has been further exacerbated by the dearth of antibiotics developed over the past 40 years. Drug-resistant bacteria have led to significant morbidity and mortality, and ever-increasing antibiotic resistance threatens to reverse many of the medical advances enabled by antibiotics over the last 40 years. The traditional strategy for combating these superbugs involves the development of new antibiotics. Yet, only two new classes of antibiotics have been introduced to the clinic over the past two decades, and both failed to combat broad spectrum gram-negative bacteria. This situation demands alternative strategies to comba... (more)
Created Date 2019
Contributor Debnath, Abhishek (Author) / Green, Alexander A (Advisor) / Liu, Yan (Committee member) / Stephanopoulos, Nicholas (Committee member) / Arizona State University (Publisher)
Subject Chemistry / Antibacterial / Biomolecule encapsulated Two dimensional material
Type Doctoral Dissertation
Extent 131 pages
Language English
Copyright
Note Doctoral Dissertation Chemistry 2019
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS


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Description Dissertation/Thesis