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Waveform Mapping and Time-Frequency Processing of Biological Sequences and Structures

Abstract Genomic and proteomic sequences, which are in the form of deoxyribonucleic acid (DNA) and amino acids respectively, play a vital role in the structure, function and diversity of every living cell. As a result, various genomic and proteomic sequence processing methods have been proposed from diverse disciplines, including biology, chemistry, physics, computer science and electrical engineering. In particular, signal processing techniques were applied to the problems of sequence querying and alignment, that compare and classify regions of similarity in the sequences based on their composition. However, although current approaches obtain results that can be attributed to key biological properties, they require pre-processing and lack robustnes... (more)
Created Date 2011
Contributor Ravichandran, Lakshminarayan (Author) / Papandreou-Suppappola, Antonia (Advisor) / Spanias, Andreas S (Advisor) / Chakrabarti, Chaitali (Committee member) / Tepedelenlioglu, Cihan (Committee member) / Lacroix, Zoe (Committee member) / Arizona State University (Publisher)
Subject Engineering / Bioinformatics / Molecular Biology / chirp signal / classification / DNA sequence alignment / Gaussian signal / protein structure alignment / querying
Type Doctoral Dissertation
Extent 138 pages
Language English
Reuse Permissions All Rights Reserved
Note Ph.D. Electrical Engineering 2011
Collaborating Institutions Graduate College / ASU Library
Additional Formats MODS / OAI Dublin Core / RIS

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Description Dissertation/Thesis