Description
The effects of iron and chromium blood concentrations have been linked to blood glucose control in diabetics. It is suggested that iron causes oxidative stress in the beta cells of the pancreas and adipocytes creating insulin insufficiency and resistance. Chromium is believed to increase the action of insulin through its biologically active molecule chromodulin. Both of these mechanisms are not clear. This 20 week case study tests the feasibility of combining iron depletion therapy followed by chromium supplementation to improve insulin sensitivity. This single case study followed a protocol of two blood donations separated by eight weeks followed by chromium supplementation of 250 µg of chromium picolinate once a day four weeks after the second blood donation. Fasting blood draws were taken at baseline, post blood draws and pre and post chromium supplementation. Results were not promising for the first hypothesis of lowering HbA1c, but the results were promising for the second hypothesis of improving insulin sensitivity by lowering the HOMA score.
Details
Title
- Iron depletion therapy and chromium supplementation for improving insulin
Contributors
- Jarrett, Nia (Author)
- Johnston, Carol (Thesis advisor)
- Lespron, Christy (Committee member)
- Mayol-Kreiser, Sandra (Committee member)
- Arizona State University (Publisher)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2015
Subjects
Resource Type
Collections this item is in
Note
- Partial requirement for: M.S., Arizona State University, 2015Note typethesis
- Includes bibliographical references (pages 47-51)Note typebibliography
- Field of study: Nutrition
Citation and reuse
Statement of Responsibility
by Nia Jarrett